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MaheshJethalia/README.md

Hi there 👋

Mahesh Jethalia

🧬 Statistical Genomics | 🔬 Computational Biology | 🎓 PhD Applicant

I work at the intersection of statistics, machine learning, and molecular biology — focused on regulatory network inference, and the identifiability and robustness of computational biology pipelines. My background spans wet-lab molecular biology and structural biology through to dry-lab transcriptomics and pan-cancer genomics analysis.

I hold a dual degree (B.Tech/M.Tech) in Biotechnology and Biochemical Engineering from IIT Kharagpur, and I'm currently applying to PhD programs working at this statistics–genomics intersection.


🔬 Research

  • First-author publication, Journal of Translational Medicine (2023) — master regulator analysis across pan-cancer TCGA data
  • Research experience at ISGlobal Barcelona, St. Jude Children's Research Hospital (with Dr. Raghvendra Mall), the University of Alberta (Newby Lab), and IIT Kharagpur (Master's thesis, Prof. Amit Das)
  • Core interests: regulatory network inference, transcriptomics, statistical identifiability of computational pipelines, pipeline robustness under model misspecification

🔧 Technical Toolkit

  • Languages: Python, R, C, Bash
  • Comp Bio / Genomics: Bioconductor, Galaxy, BLAST, TCGA pipelines, regulatory network inference
  • ML / Stats: scikit-learn, TensorFlow, statistical modeling, identifiability analysis
  • Structural Biology: MD simulations, UCSF ChimeraX
  • Wet Lab: PCR, Western/Southern blot, ELISA, mammalian & microbial cell culture, plasmid work
  • Tools: Git, Linux

📫 Find Me

Open to research collaborations and conversations on statistical genomics, regulatory networks, and computational biology pipelines.

Pinned Loading

  1. raghvendra5688/INV_Analysis raghvendra5688/INV_Analysis Public

    PANcancer invasiveness analysis using consensus frameworks of RGBM + FGSEA, RGBM + Viper, ARACNE + FGSEA and ARACNE + Viper

    HTML 2 2

  2. INV_Analysis INV_Analysis Public

    Forked from raghvendra5688/INV_Analysis

    PANcancer invasiveness analysis using consensus frameworks of RGBM + FGSEA, RGBM + Viper, ARACNE + FGSEA and ARACNE + Viper

    HTML

  3. ICR_Analysis ICR_Analysis Public

    Forked from raghvendra5688/ICR_Analysis

    Network based identification of key master regulators for immunologic constant of rejection

    R