detectIVe

An R Shiny-based application for interactive visualization and analysis of patch-clamp data, particularly focused on detecting and analyzing IV relations.

Overview

detectIVe provides researchers with a powerful, user-friendly interface for processing, analyzing, and visualizing patch-clamp data. The application features an intuitive workflow for signal detection, quantification, and export.

Features

• Interactive data visualization
• Time-series analysis of patch-clamp signals
• Automated signal detection algorithms
• Manual annotation and correction tools
• Multiple export formats
• Batch processing capabilities
• Publication-ready plots and figures
• Real-time data exploration

Requirements

For Running from Source

• R (version 4.2.3 or higher recommended)
• RStudio (optional but recommended)
• Required R packages (installed via prepareDetectIVe.r)

For Standalone Installation

• Windows operating system
• R version 4.2.3

Installation

Option 1: Standalone Windows Application

1. Download the installer from the Installer directory (if available)
2. Run the installer executable
3. Follow the installation wizard
4. Launch detectIVe from the Start Menu

Option 2: Running from Source

1. Clone this repository
2. Open R or RStudio
3. Set working directory to the repository folder
4. Run the preparation script:

   source("prepareDetectIVe.r")

Project Structure

detectIVe/
├── ui.R                      # User interface definition
├── server.R                  # Server logic and data processing
├── globalStuff.r             # Global variables and shared functions
├── prepareDetectIVe.r        # Dependency installation script
├── rInno.R                   # Standalone installer builder
├── DetectIVe2.iss            # Inno Setup configuration
├── detectIVe_manual.pdf      # Comprehensive user manual
├── detectIVe 2.0.Rproj       # RStudio project file
├── About/                    # Application information and credits
├── www/                      # Web assets (CSS, images, JavaScript)
├── screenshots/              # Application interface screenshots
└── Installation Guide.txt    # Quick installation instructions

File Descriptions

File	Purpose
ui.R	Defines the user interface layout and controls
server.R	Contains all server-side logic and data processing functions
globalStuff.r	Global variables, utility functions, and shared constants
prepareDetectIVe.r	Installs and loads all required R package dependencies
rInno.R	Script to build a standalone Windows installer using RInno
DetectIVe2.iss	Inno Setup configuration for the Windows installer
detectIVe 2.0.Rproj	RStudio project file for development

Usage Guide

Basic Workflow

For detailed step-by-step instructions, see the user manual.

Documentation

User Manual

The comprehensive user manual (detectIVe_manual.pdf) includes:

• Complete installation instructions
• Detailed feature descriptions
• Step-by-step analysis workflows
• Troubleshooting guide
• Example datasets and use cases
• FAQ section

Screenshots

Sample screenshots demonstrating the application interface are available in the screenshots/ directory.

Installation Guide

Quick installation reference: Installation Guide.txt

Building a Standalone Installer

To create your own Windows installer:

# Open R and run:
source("rInno.R")

This uses the RInno package to:

• Bundle R and all dependencies
• Create a self-contained executable
• Generate an installer wizard
• Enable automatic updates

Dependencies

Key R packages used (automatically installed):

• shiny - Interactive web application framework
• ggplot2 - Graphics and visualization
• data.table - Efficient data manipulation
• Plus additional supporting packages

Full dependency list in prepareDetectIVe.r

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Happy analyzing! 🔬✨