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Bioinformatics Tutorials

Hands-on tutorials for common population- and conservation-genomics analyses, written for students and collaborators working with non-model / wildlife whole-genome data. Worked examples use Neotropical wildlife (e.g. Neofelis) as case studies.

Contents

File Topic
Heterozigosity_angsd tutorial.md Per-individual heterozygosity from BAMs with ANGSD (SAF → realSFS), suitable for low-coverage data
PSMC tutorial.md Reconstructing historical effective population size with the PSMC coalescent model
SNP density tutorial.md Computing and interpreting SNP density along the genome
Neofelis_snpdenPlot_chr.R R: SNP-density plot by chromosome
Neofelis_snpdenPlot_sample.R R: SNP-density plot by sample
StringDB.md Building protein–protein interaction networks with the STRING database

How to use

Each .md file is a self-contained walkthrough — open it and follow along. The R scripts are run with Rscript <script>.R and will install the CRAN packages they need on first run.

Related

  • popgen-scripts — standalone, parameterized versions of several of these analyses as reusable command-line tools.
  • Congen2025 — the full Conservation Genomics Workshop curriculum these tutorials feed into.

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Hands-on bioinformatics tutorials: heterozygosity (ANGSD), PSMC, SNP density, STRING networks.

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