Adapt Sequence properties block to dms data

.changeset/adapt-synthetic-repertoire-profiler.md

@@ -0,0 +1,14 @@
+---
+'@platforma-open/milaboratories.sequence-properties.model': patch
+'@platforma-open/milaboratories.sequence-properties.workflow': patch
+'@platforma-open/milaboratories.sequence-properties.ui': patch
+---
+
+Support `synthetic-repertoire-profiler` (amplicon) variant datasets:
+
+- `detectMode` now recognizes the profiler's `pl7.app/variantKey` axis (axis domain `pl7.app/repertoire/extractionRunId`) as a new `"amplicon"` mode, instead of falling through to the "no recognized sequence key axis" panic.
+- Amplicon runs the same whole-sequence physicochemical computation as peptide mode (the Python engine runs it under its `peptide` path), reading the whole-variant amino-acid sequence (`pl7.app/feature: "amplicon-sequence"`).
+- Output property columns (and the AA-fraction column) are labeled with the `amplicon-sequence` feature instead of `peptide`, so they attach to the correct entity.
+- The UI's default scatter/histogram axes are amplicon-aware (charge / hydrophobicity on the `amplicon-sequence` feature).
+
+Per-region properties for amplicon (using the profiler's region subsequences) are out of scope here — whole-sequence descriptors only.

block/package.json

@@ -4,7 +4,7 @@
   "scripts": {
     "build": "shx rm -rf ./block-pack && block-tools pack",
     "mark-stable": "block-tools mark-stable -r 's3://milab-euce1-prod-pkgs-s3-block-registry/pub/releases/?region=eu-central-1'",
-    "prepublishOnly": "block-tools pack && block-tools publish --unstable -r 's3://milab-euce1-prod-pkgs-s3-block-registry/pub/releases/?region=eu-central-1'",
+    "prepublishOnly": "block-tools pack && block-tools publish --unstable -r 's3://milab-euce1-prod-pkgs-s3-block-registry/pub/releases/?region=eu-central-1'  --registry-serve-url https://blocks.pl-open.science",
     "do-pack": "shx rm -f *.tgz && block-tools pack && pnpm pack && shx mv *.tgz package.tgz"
   },
   "files": [

model/src/types.ts

@@ -35,6 +35,10 @@ export type BlockArgs = {
 
 export type WorkflowMode =
   | "peptide"
+  // synthetic-repertoire-profiler amplicon variants: whole-sequence properties
+  // on the variant's amino-acid sequence (same math as peptide mode, labeled
+  // with the "amplicon-sequence" feature instead of "peptide").
+  | "amplicon"
   | "antibody_tcr_universal"
   | "antibody_tcr_legacy_bulk"
   | "antibody_tcr_legacy_sc";