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operator-geometry

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Anas-Enoch / tumor-immune-operator-geometry

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Operator-theoretic spatial biology framework for tumor–immune interface analysis using Hodge decomposition, antisymmetric commutator geometry, and graph operator dynamics. Validated across HCC, IMC, CABO/NIVO, and a pan-cancer Visium cohort (26 sections, 118k+ spots, 6 cancer types).

bioinformatics systems-biology hcc spatial-transcriptomics cancer-immunotherapy graph-laplacian visium hodge-decomposition computational-oncology tumor-immune-microenvironment operator-geometry
  • Updated May 21, 2026
  • Python

Anas-Enoch / Pathway_Identifiability

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Computational framework for metabolite acquisition prioritization under partial pathway observability using operator-based structural ambiguity reduction.

benchmarking machine-learning bioinformatics reproducible-research systems-biology computational-biology metabolomics observability pathway-analysis biological-networks network-biology graph-learning metabolic-networks computational-metabolomics operator-geometry metabolite-acquisition pathway-identifiability
  • Updated May 21, 2026
  • Python

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